The Brain Imaging and Neuropsychology (BraIN) Laboratory at UW-Milwaukee. The primary focus of the BraIN Lab is on the neurocognitive consequences of chronic drug use during adolescence and young adulthood. More specifically, using magnetic resonance imaging (structural MRI, functional MRI and diffusion tensor imaging) and neuropsychological assessment, we examine the effects of marijuana, alcohol, nicotine and ecstasy on brain structure and function. We also attempt to explain individual differences by examining whether gender, genetics (e.g., 5-HTTLPR, BDNF, COMT, NRG1, FAAH, KIBRA), or lifestyle factors (body mass index, cardiorespiratory health, activity markers) moderate these effects. We are also interested in studying these issues in healthy developing teens and young adults. Currently, we are running a NIH/NIDA funded study (R01 DA030354) examining whether physical activity levels or cardiorespiratory fitness moderate the effects of chronic marijuana use on frontolimbic connectivity in teens and emerging adults.
