I examine brain-behavior relationships in clinical populations using cognitive and affective neuroscience techniques, particularly multimodal neuroimaging and neuropsychological assessments. My FMRI work includes paradigm development with a focus on clinically relevant constructs (e.g., objective assessments of subjective states, prediction of treatment outcome). Recent studies include the use of functional neuroimaging markers to predict smoking cessation outcome; functional, structural and prefusion MRI correlates of cognitive function in cardiovascular disease; the effects of early life stress on adult cognitive function; cue reactivity in obesity and nicotine dependence; and working memory and information processing speed in subcortical disease processes.
