My research uses the principles/methods of developmental psychopathology to understand the etiology of ADHD and disruptive behavior disorders, particularly within the context of longitudinal designs. This work has 3 principle components: (1) Testing gene-environment correlations and interactions for child conduct problems and negative maternal parenting behavior; (2) Identifying predictors of persistence and desistance of child conduct problems, exploring sex differences in antisocial behavior, and developing clinically significant measures of child outcome; and (3) Using translational research strategies to identify strong phenotypes that are impaired across multiple forms of psychopathology.